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Catalog Number | orb1697923 |
---|---|
Category | Small Molecules |
Description | GSK1838705A |
CAS Number | 1116235-97-2 |
Purity | 99.63% |
MW | 532.57 |
SMILES | C(CN(C)C)(=O)N1C=2C(=CC(OC)=C(NC3=NC(NC4=C(C(NC)=O)C(F)=CC=C4)=C5C(=N3)NC=C5)C2)CC1 |
Formula | C27H29FN8O3 |
Biological Activity | GSK1838705A is an effective IGF-1R inhibitor (IC50: 2.0 nM), modestly potent to IR (IC50: 1.6 nM) and ALK (IC50: 0.5 nM), respectively, and little inhibition to other protein kinases. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1116235-97-2 |
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