GSK-3β inhibitor 17

• Catalog Number: orb2646324
• Category: Small Molecules
• Description: GSK-3β Inhibitor 17 (compound 5 n) reduces the expression of p-p65 and KIM-1 proteins in a dose-dependent manner (16, 32, 64 µM) induced by cisplatin. Additionally, at a concentration of 32 µM, it decreases the levels of TNF-α, IL-1β, IL-6, and MCP-1 mRNA in an acute kidney injury (AKI) model of HK-2 cells triggered by cisplatin.
• CAS Number: 2521624-67-7
• Purity: 98.00%
• MW: 617.58
• SMILES: O=C(OC)C=1SC(=CC1)S(=O)(=O)NC=2C=CC(=CC2)C3=NC(=NO3)C=4C=CN=C(C4)NC5=CC=C(OC(F)(F)F)C=C5
• Formula: C₂₆H₁₈F₃N₅O₆S₂
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.