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GSK-3β inhibitor 15
Catalog Number: orb2278340
| Catalog Number | orb2278340 |
|---|---|
| Category | Small Molecules |
| Description | GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-induced iNOS expression, demonstrating neuroprotective properties against Aβ 1-42-induced neurotoxicity and indicating potential utility in Alzheimer's disease (AD) research [1]. |
| Purity | 98.00% |
| MW | 352.41 |
| Formula | C17H16N6OS |
| Biological Activity | GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-induced iNOS expression. It demonstrates neuroprotective properties against Aβ 1-42-induced neurotoxicity, indicating its potential utility in Alzheimer's disease (AD) research [1]. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
