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Catalog Number | orb320200 |
---|---|
Category | Small Molecules |
Description | GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). |
CAS Number | [874119-56-9] |
MW | 513.32 |
SMILES | CC1=C(C(N=C(N1)C2=CC(=NC=C2)Cl)C3=C(C=C(C=C3)Cl)F)C(=O)NC4=C(C=C5C(=C4)C=NN5)F |
Formula | C24H16Cl2F2N6O |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Chemical structure of GSK-25
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