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Catalog Number | orb1302820 |
---|---|
Category | Small Molecules |
Description | GSK-25 |
CAS Number | 874119-56-9 |
Purity | 99.14% |
MW | 513.33 |
SMILES | C(NC=1C=C2C(=CC1F)NN=C2)(=O)C=3C(NC(=NC3C)C=4C=C(Cl)N=CC4)C5=C(F)C=C(Cl)C=C5 |
Formula | C24H16Cl2F2N6O |
Biological Activity | GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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