GSK-114

• Catalog Number: orb1305989
• Category: Small Molecules
• Description: GSK-114
• CAS Number: 1301761-96-5
• Purity: 98.03%
• MW: 417.48
• SMILES: N(C=1C2=C(C=C(OC)C(OC)=C2)N=CN1)C3=C(N(C)C)C=CC(S(NC)(=O)=O)=C3
• Formula: C₁₉H₂₃N₅O₄S
• Biological Activity: GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.