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GSK-114
Catalog Number: orb1305989
| Catalog Number | orb1305989 |
|---|---|
| Category | Small Molecules |
| Description | GSK-114 |
| CAS Number | 1301761-96-5 |
| Purity | 99.66% |
| MW | 417.48 |
| SMILES | CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3cc(OC)c(OC)cc23)c1 |
| Formula | C19H23N5O4S |
| Biological Activity | GSK-114 is a selective inhibitor of TNNI3 interacting kinase (TNNI3K) with an IC50 of 25 nM, 40-fold significant bias for TNNI3K compared to B-Raf with an IC50 of 1000 nM, so GSK-114 has excellent Broad-spectrum kinase selectivity and sufficient oral exposure enable use in cellular and in vivo studies. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
GSK-114 [orb746353]
[1301761-96-5]
417.48202252388
C19H23N5O4S
1 ml x 10 mm (in DMSO), 250 mg, 100 mg, 1 g
