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    GPR40 agonist 5

    GPR40 agonist 5

    Catalog Number: orb1687502

    DispatchUsually dispatched within 6-8 weeks
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    Catalog Numberorb1687502
    CategorySmall Molecules
    DescriptionGPR40 agonist 5
    CAS Number2443384-60-7
    Purity98%
    MW440.49
    SMILESO=C(O)CC(C#CC)C1=CC=C(OCC=2C=CC3=NC(=CN3C2)C=4C=CC(OC)=CC4)C=C1
    FormulaC27H24N2O4
    Biological ActivityGPR40 agonist 5 (compound I-14) is an orally active and potent GPR40 (G protein coupled receptor 40) agonist, with an EC 50 of 47 nM. GPR40 agonist 5 decreases the levels of blood glucose and improves the glucose tolerance. GPR40 agonist 5 has sufficient effectiveness for the control of hyperglycemia state in type 2 diabetic mice [1].
    StorageStore at -20°C for 12 months.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • AMG-837 [orb251431]

      [865231-46-5]

      438.44

      C26H21F3O3

      10 mM * 1 mL in DMSO, 1000 mg, 250 mg, 100 mg
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