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Catalog Number | orb1308262 |
---|---|
Category | Small Molecules |
Description | GNF351 |
CAS Number | 1227634-69-6 |
Purity | 99.04% |
MW | 411.5 |
SMILES | CC(C)n1cnc2c(NCCc3c[nH]c4ccccc34)nc(nc12)-c1cncc(C)c1 |
Formula | C24H25N7 |
Biological Activity | GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |