GNF351

• Catalog Number: orb1308262
• Category: Small Molecules
• Description: GNF351
• CAS Number: 1227634-69-6
• Purity: 99.04%
• MW: 411.5
• SMILES: N(CCC=1C=2C(NC1)=CC=CC2)C3=C4C(N(C(C)C)C=N4)=NC(=N3)C=5C=C(C)C=NC5
• Formula: C₂₄H₂₅N₇
• Biological Activity: GNF351 is a full antagonist of the aryl hydrocarbon receptor (AHR)with the capacity to inhibit both DRE-dependent and -independent activity. GNF351 is minimal toxicity in mouse or human keratinocytes. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR (IC50: 62 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.