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Catalog Number | orb1301772 |
---|---|
Category | Small Molecules |
Description | GNE-6640 |
CAS Number | 2009273-67-8 |
Purity | 99.59% |
MW | 330.38 |
SMILES | C(C)C=1C(=C(N)N=CC1C=2C=C3C(=CC2)NN=C3)C4=CC=C(O)C=C4 |
Formula | C20H18N4O |
Biological Activity | GNE-6640 is a non-covalent inhibitor targeting ubiquitin specific peptidase 7 (USP7), exhibiting IC50 values of 0.75 μM for full-length USP7, 0.43 μM for the USP7 catalytic domain, 20.3 μM for full-length USP43, and 0.23 μM for Ub-MDM2, respectively. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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