GNE-049

• Catalog Number: orb1707262
• Category: Small Molecules
• Description: GNE-049
• CAS Number: 1936421-41-8
• MW: 510.58
• SMILES: C(C)(=O)N1CC=2C(=NN(C2CC1)C3CCOCC3)N4C=5C(=CC(=C(C(F)F)C5)C6=CN(C)N=C6)CCC4
• Formula: C₂₇H₃₂F₂N₆O₂
• Biological Activity: GNE-049 is a highly potent and selective inhibitor of CBP (IC50: 1.1 nM in TR-FRET assay). GNE-049 also inhibits BRET and BRD4(1) (IC50s: 12 nM and 4200 nM, respectively).
• Note: For research use only
• Expiration Date: 12 months from date of receipt.