Glucocorticoid receptor modulator 1

• Catalog Number: orb1745131
• Category: Small Molecules
• Description: Glucocorticoid receptor modulator 1
• CAS Number: 2868357-11-1
• MW: 470.97
• SMILES: C(=O)(N1C=2C(=CC(NS(=O)(=O)C3=C(OC)C=C(C)C(Cl)=C3)=CC2)CCC1)C4=CC=CC=C4
• Formula: C₂₄H₂₃ClN₂O₄S
• Biological Activity: Glucocorticoid receptor modulator 1 is a potent, orally active, non-steroidal selective glucocorticoid receptor modulator, exhibiting IC50 values of 9 nM and 130 nM against NF-κB and AP-1, respectively. It effectively reduces the expression of inflammatory factors such as IL-6, IL-1β, and TNF-α, and alleviates dermatitis in mice.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.