GLS1 Inhibitor

• Catalog Number: orb1693054
• Category: Small Molecules
• Description: GLS1 Inhibitor
• CAS Number: 1832646-52-2
• Purity: 98%
• MW: 411.48
• SMILES: N([C@H]1CN(CC1)C2=CC=CN=N2)C=3SC(NC([C@@H](OC)C4=CC=CC=C4)=O)=NN3
• Formula: C₁₉H₂₁N₇O₂S
• Biological Activity: GLS1 inhibitor is an inhibitor of glutaminase 1 (GLS1; IC50= 0.021 μM).1It inhibits the growth of NCI H1703 non-small cell lung cancer (NSCLC) cellsin vitro(GI50= 0.011 μM). GLS1 inhibitor (100 mg/kg) reduces tumor growth, increases tumor levels of glutamine, and decreases tumor levels of glutamate and aspartate in an NCI H1703 mouse xenograft model.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.