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Catalog Number | orb1707270 |
---|---|
Category | Small Molecules |
Description | Glesatinib hydrochloride |
CAS Number | 1123838-51-6 |
Purity | 98% |
MW | 656.16 |
SMILES | Cl.COCCNCc1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)c2s1 |
Formula | C31H28ClF2N5O3S2 |
Biological Activity | Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO. Glesatinib hydrochloride is also a tyrosine kinase inhibitor. It antagonizes P-glycoprotein mediated multidrug resistance (MDR) in NSCLC. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |