GGTI-2418

• Catalog Number: orb1709612
• Category: Small Molecules
• Description: GGTI-2418
• CAS Number: 501010-06-6
• MW: 441.52
• SMILES: C([C@@H]1N(C(N[C@@H](CC(C)C)C(O)=O)=O)CCN(CC2=C(C)N=CN2)C1=O)C3=CC=CC=C3
• Formula: C₂₃H₃₁N₅O₄
• Biological Activity: GGTI-2418 is a highly potent, competitive, and selective inhibitor of geranylgeranyltransferase I (GGTase I), showing inhibitory activities with IC50 values of 9.5 nM for GGTase I and 53 μM for FTase, respectively. Additionally, it enhances p27(Kip1) expression and induces significant regression of breast tumors.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.