You have no items in your shopping cart.
Cart summary
GFB-8438
Catalog Number: orb746451
| Catalog Number | orb746451 |
|---|---|
| Category | Small Molecules |
| Description | GFB-8438 is a potent and subtype selective TRPC5 inhibitor, with IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively. GFB-8438 shows excellent selectivity against TRPC6, other TRP family members, NaV 1.5, as well as limited activity against the hERG channel. GFB-8438 protects mouse podocytes from injury induced by protamine sulfate model. |
| CAS Number | [2304549-73-1] |
| MW | 386.76 |
| SMILES | O=C1N(CC2C(C(F)(F)F)=CC=CC=2)CCN(C2C=NNC(=O)C=2Cl)C1 |
| Formula | C16H14ClF3N4O2 |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
