Gemfibrozil-d6

• Catalog Number: orb1738174
• Category: Small Molecules
• Description: Gemfibrozil-d6
• CAS Number: 1184986-45-5
• Purity: 0.98
• MW: 256.37
• SMILES: O(CCCC(C(O)=O)(C([2H])([2H])[2H])C([2H])([2H])[2H])C1=C(C)C=CC(C)=C1
• Formula: C₁₅H₁₆D₆O₃
• Biological Activity: Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif ligand 2 (CCL2) in ApoE-/- mice. Formulations containing gemfibrozil have been used in the treatment of high cholesterol.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.