You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1738174 |
---|---|
Category | Small Molecules |
Description | Gemfibrozil-d6 |
CAS Number | 1184986-45-5 |
Purity | 0.98 |
MW | 256.37 |
SMILES | O(CCCC(C(O)=O)(C([2H])([2H])[2H])C([2H])([2H])[2H])C1=C(C)C=CC(C)=C1 |
Formula | C15H16D6O3 |
Biological Activity | Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif ligand 2 (CCL2) in ApoE-/- mice. Formulations containing gemfibrozil have been used in the treatment of high cholesterol. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating