Gefitinib hydrochloride

Catalog Number: orb1909577

Catalog Number	orb1909577
Category	Small Molecules
Description	Gefitinib hydrochloride
CAS Number	184475-55-6
MW	483.36
SMILES	Cl.FC1=CC=C(C=C1Cl)NC=2N=CN=C3C=C(OC)C(OCCCN4CCOCC4)=CC32
Formula	C₂₂H₂₅Cl₂FN₄O₃
Biological Activity	Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent and orally active EGFR tyrosine kinase inhibitor (EGFR-TKI) (IC 50 = 33 nM) that selectively inhibits EGF-stimulated tumor cell growth (IC 50 = 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy, which has antitumour activity [1] [2].
Note	For research use only
Expiration Date	12 months from date of receipt.

Gefitinib hydrochloride [orb1941065]
Purity:
> 98% (HPLC)
CAS Number:
184475-55-6
Sizes Available: 1 g, 500 mg, 200 mg, 100 mg
Gefitinib N-oxide hydrochloride [orb1983583]
MW:
517.59
Formula:
C₂₂H₂₄ClFN₄O₄₁.5HCl
Gefitinib hydrochloride [orb611388]
CAS Number:
[184475-55-6]
MW:
483.3633
Formula:
C₂₂H₂₄N₄O₃FCL.HCL
Sizes Available: 1 g, 250 mg, 100 mg
Gefitinib hydrochloride [orb1893618]
CAS Number:
184475-55-6
Sizes Available: 500 mg
Gefitinib hydrochloride [orb1893619]
CAS Number:
184475-55-6
Sizes Available: 1000 mg

Purity:	> 98% (HPLC)
CAS Number:	184475-55-6

MW:	517.59
Formula:	C₂₂H₂₄ClFN₄O₄₁.5HCl