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GCHFR Antibody / GFRP
Catalog Number: orb1825430
| Catalog Number | orb1825430 |
|---|---|
| Category | Antibodies |
| Description | GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer. |
| Species/Host | Mouse |
| Clonality | Monoclonal |
| Clone Number | GCHFR/7731 |
| Tested applications | IHC-P |
| Reactivity | Human |
| Isotype | Mouse IgG2, kappa |
| Immunogen | A recombinant fragment of human protein was used as the immunogen for the GCHFR antibody. |
| Antibody Type | Primary Antibody |
| Dilution range | Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT |
| Conjugation | Unconjugated |
| Formula | 1 mg/ml in 1X PBS; BSA free, sodium azide free |
| Hazard Information | This GFRP antibody is available for research use only. |
| UniProt ID | P30047 |
| Storage | Aliquot the GFRP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
IHC staining of FFPE human liver in HCC with GFRP antibody (clone GCHFR/7731). HIER: boil tissue sections in pH9 10 mM Tris with 1 mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free GFRP antibody (clone GCHFR/7731) as confirmation of integrity and purity.
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