gardiquimod TFA salt

• Catalog Number: orb1909038
• Category: Small Molecules
• Description: gardiquimod TFA salt
• CAS Number: 1159840-61-5
• MW: 541.44
• SMILES: CCNCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
• Formula: C₂₁H₂₅F₆N₅O₅
• Biological Activity: Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM. Gardiquimod diTFA could function as both an immune system modifier and a reverse transcriptase inhibitor as a novel therapeutic agent to block systemic and mucosal transmission of HIV-1.[1] [2].
• Note: For research use only
• Expiration Date: 12 months from date of receipt.