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Catalog Number | orb1089602 |
---|---|
Category | Small Molecules |
Description | Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial. |
CAS Number | [1507930-57-5] |
MW | 1161.436753 |
SMILES | O=C([C@H]([C@@H](C)CC)NC([C@H](CCC(=O)O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H](CCCCN)N)=O)=O)=O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)O)CCCCN)=O)CC1C=CC=CC=1)=O)CCCCN)=O)CCCCN |
Formula | C55H96N14O13 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 95% by hplc | |
2703.28 Da | |
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Lys-Gln-Ile-Glu-Ile-Lys-Lys-Phe-Lys-OH |
> 98% (HPLC) | |
1507930-57-5 |
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