FXR agonist 3

• Catalog Number: orb1982428
• Category: Small Molecules
• Description: FXR agonist 3
• MW: 522.43
• SMILES: COC1=C(OCC2=CC=CC(C)=C2)C3=C[N+](CCC4=C5C=C(OC)C(OC)=C4)=C5C=C3C=C1.[Br-]
• Formula: C₂₈H₂₈BrNO₄
• Biological Activity: FXR agonist 3, an anti-NASH (Non-Alcoholic Steatohepatitis) agent, functions by activating FXR. It demonstrates anti-fibrogenic activity by inhibiting the expression of COL1A1, TGF-β1, α-SMA, and TIMP1. Additionally, it significantly mitigates liver steatosis and inflammation and enhances the liver fibrosis level [1].
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.