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Catalog Number | orb1982428 |
---|---|
Category | Small Molecules |
Description | FXR agonist 3 |
MW | 522.43 |
SMILES | COC1=C(OCC2=CC=CC(C)=C2)C3=C[N+](CCC4=C5C=C(OC)C(OC)=C4)=C5C=C3C=C1.[Br-] |
Formula | C28H28BrNO4 |
Biological Activity | FXR agonist 3, an anti-NASH (Non-Alcoholic Steatohepatitis) agent, functions by activating FXR. It demonstrates anti-fibrogenic activity by inhibiting the expression of COL1A1, TGF-β1, α-SMA, and TIMP1. Additionally, it significantly mitigates liver steatosis and inflammation and enhances the liver fibrosis level [1]. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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