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Catalog Number | orb1304860 |
---|---|
Category | Small Molecules |
Description | Fraxetin |
CAS Number | 574-84-5 |
Purity | 99.76% |
MW | 208.17 |
SMILES | COc1cc2ccc(=O)oc2c(O)c1O |
Formula | C10H8O5 |
Biological Activity | Fraxetin (7,8-dihydroxy-6-methoxy coumarin) has dual-antioxidative ,hepatoprotective and antihyperglycemic functions, it shows potent protective effects against CCl4 induced oxidative stress and hepatic fibrosis, has a marked inhibitory effect on S.aureus proliferation. It increased the level of Nrf2/ARE, and HO-1, inhibit the formation of ROS, cytochrome c release, activation of caspase-3 and 9, and suppressed the up-regulation of Bax. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |