You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1694352 |
---|---|
Category | Small Molecules |
Description | FR900098 (sodium salt) |
CAS Number | 73226-73-0 |
Purity | 98% |
MW | 220.117 |
SMILES | [Na].CC(=O)N(O)CCCP(O)(O)=OjcExt:v:0:0 |
Formula | C5H12NNaO5P |
Biological Activity | FR900098 is a derivative of fosmidomycin that has antimalarial activity (IC50s = 170, 170, and 90 nM for HB3, A2, and Dd2 P. falciparum strains, respectively). FR900098 inhibits DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis, in vitro in a dose-dependent manner. FR900098 (>10 mg/kg, i.p.) eradicated P. vinckei parasites within four days in mice. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
Filter by Rating