FOXL2 Antibody

• Catalog Number: orb1823587
• Category: Antibodies
• Description: FOXL2 is a critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. It prevents trans-differentiation of ovary to testis through transcriptional repression of the sertoli cell-promoting gene SOX9. FOXL2 is mainly expressed in ovary, parathyroid gland and sex cord-stromal tumors. FOXL2 is generally used for diagnosis of sex cord-stromal tumors with Inhibin, Calretinin and SF-1.
• Species/Host: Rabbit
• Clonality: Recombinant
• Clone Number: FOXL2/7989R
• Tested applications: IHC-P
• Reactivity: Human
• Isotype: Rabbit IgG, kappa
• Immunogen: Recombinant full-length human FOXL2 protein was used as the immunogen for the recombinant FOXL2 antibody.
• Dilution range: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This recombinant FOXL2 antibody is available for research use only.
• UniProt ID: P58012
• Storage: Aliquot the recombinant FOXL2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

FFPE human ovarian adult granulosa cell tumor with recombinant FOXL2 antibody (clone FOXL2/7989R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human ovarian adult granulosa cell tumor tissue with recombinant FOXL2 antibody (clone FOXL2/7989R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

IHC staining of FFPE human parathyroid tissue with recombinant FOXL2 antibody (clone FOXL2/7989R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.