Fosmidomycin

• Catalog Number: orb2564498
• Category: Small Molecules
• Description: Fosmidomycin is an orally administered antibiotic that demonstrates antimalarial properties by inhibiting 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase. It effectively inhibits the P. falciparum strains 3D7, HB3, Dd2, and A2, with IC 50 values of 150, 71, 170, and 150 ng/mL, respectively. Fosmidomycin works synergistically with Clindamycin and alleviates malaria in a mouse model.
• CAS Number: 66508-53-0
• Purity: 98.00%
• MW: 183.10
• SMILES: O=CN(O)CCCP(=O)(O)O
• Formula: C₄H₁₀NO₅P
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.