Fosaprepitant-d4 Dimeglumine

• Catalog Number: orb2299506
• Category: Small Molecules
• Description: Fosaprepitant-d4 Dimeglumine is a deuterated compound of Fosaprepitant Dimeglumine. Fosaprepitant Dimeglumine has a CAS number of 265121-04-8. Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
• Purity: 98.00%
• MW: 1008.86
• SMILES: C[C@@H](O[C@H]1OC([2H])([2H])C([2H])([2H])N(CC2NC(=O)N(P(O)(O)=O)N=2)[C@H]1C1C=CC(F)=CC=1)C1C=C(C(F)(F)F)C=C(C(F)(F)F)C=1.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• Formula: C₃₇H₅₂D₄F₇N₆O₁₆P
• Biological Activity: Fosaprepitant-d4 Dimeglumine is a deuterated compound of Fosaprepitant Dimeglumine. Fosaprepitant Dimeglumine has a CAS number of 265121-04-8. Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.