Fluorofenidone

• Catalog Number: orb1308299
• Category: Small Molecules
• Description: Fluorofenidone
• CAS Number: 848353-85-5
• Purity: 99.87%
• MW: 203.21
• SMILES: O=C1N(C2=CC(F)=CC=C2)C=C(C)C=C1
• Formula: C₁₂H₁₀FNO
• Biological Activity: Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway. Fluorofenidone is an analogue of AMR69. Which displays equivalent lower toxicity, antifibrotic activity, and longer half-life.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.