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Flavopiridol hydrochloride
Catalog Number: orb1305264
| Catalog Number | orb1305264 |
|---|---|
| Category | Small Molecules |
| Description | Flavopiridol hydrochloride |
| CAS Number | 131740-09-5 |
| Purity | 99.88% |
| MW | 438.3 |
| SMILES | Cl.CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl |
| Formula | C21H21Cl2NO5 |
| Biological Activity | Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 expression, resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
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Flavopiridol Hydrochloride [orb341697]
[131740-09-5]
438.3011
C21H21CL2NO5
1 ml x 10 mm (in DMSO), 1 g, 100 mg, 250 mg
