You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1306378 |
---|---|
Category | Small Molecules |
Description | Finerenone |
CAS Number | 1050477-31-0 |
Purity | 99.65% |
MW | 378.42 |
SMILES | O(CC)C1=C2[C@@H](C(C(N)=O)=C(C)NC2=C(C)C=N1)C3=C(OC)C=C(C#N)C=C3 |
Formula | C21H22N4O3 |
Biological Activity | Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862) displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
> 98% (HPLC) | |
1050477-31-0 |
Filter by Rating