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Finerenone-d5
Catalog Number: orb2280934
| Catalog Number | orb2280934 |
|---|---|
| Category | Small Molecules |
| Description | Finerenone-d5 is a deuterated compound of Finerenone. Finerenone has a CAS number of 1050477-31-0. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). |
| Purity | 98.00% |
| MW | 383.46 |
| SMILES | N#CC1=CC=C([C@H]2C(C(OC(C([2H])([2H])[2H])([2H])[2H])=NC=C3C)=C3NC(C)=C2C(N)=O)C(OC)=C1 |
| Formula | C21H17D5N4O3 |
| Biological Activity | Finerenone-d5 is a deuterated compound of Finerenone. Finerenone has a CAS number of 1050477-31-0. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
