Filgotinib maleate

• Catalog Number: orb1686221
• Category: Small Molecules
• Description: Filgotinib maleate
• CAS Number: 1802998-75-9
• Purity: 98%
• MW: 541.58
• SMILES: OC(=O)\C=C/C(O)=O.O=C(Nc1nc2cccc(-c3ccc(CN4CCS(=O)(=O)CC4)cc3)n2n1)C1CC1
• Formula: C₂₅H₂₇N₅O₇S
• Biological Activity: Filgotinib (maleate) is a selective, orally active JAK1 inhibitor that effectively inhibits the activity of JAK1 (IC50: 10 nM), JAK2 (IC50: 28 nM), JAK3 (IC50: 810 nM) and TYK2 (IC50: 116 nM). maleate) can be used to study rheumatoid arthritis (RA) and Crohn's disease.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.