Fidaxomicin

• Catalog Number: orb864224
• Category: Small Molecules
• Description: Fidaxomicin is a macrocyclic antibiotic, isolated from actinomycete Dactylosporangium aurantiacum. Fidaxomicin is an RNA polymerase inhibitor that has a narrow antibiotic activity spectrum and is not readily absorbed into the blood circulatory system.This anti-bacterial agent is almost Clostridium difficile specific in the colon, and has minimal effect to the intestinal microbial flora.
• CAS Number: 873857-62-6
• Purity: ≥98%
• MW: 1058.05
• SMILES: CCC1C=C(C(CC=CC=C(C(=O)OC(CC=C(C=C(C1OC2C(C(C(C(O2)(C)C)OC(=O)C(C)C)O)O)C)C)C(C)O)COC3C(C(C(C(O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)C
• Chemical Name: [(2R,3S,4S,5S,6R)-6-[[(3E,5E,8S,9E,11S,12R,13E,15E,18S)-12-[(2R,3S,4R,5S)-3,4-dihydroxy-6,6-dimethyl-5-(2-methylpropanoyloxy)oxan-2-yl]oxy-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-2-oxo-1-oxacyclooctadeca-3,5,9,13,15-pentaen-3-yl]methoxy]-4-hydroxy-5-methoxy-2-methyloxan-3-yl] 3,5-dichloro-2-ethyl-4,6-dihydroxybenzoate
• Hazard Information: Non-Toxic
• Solubility (25°C): Insoluble in water, soluble in CHCl3(10 mg/ml), methanol(10 mg/ml), DMSO(1mg/ml).
• Storage: Storage Temp: -20°C
• Alternative names: Clostomicin B1, Dificid, Dificlir, lipiarmicin lip
• Note: For research use only
• Expiration Date: 12 months from date of receipt.