FGIN-1-27

• Catalog Number: orb1473073
• Category: Small Molecules
• Description: FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO).FGIN-1-27 inhibited Th17 cell differentiation, significantly downregulated the expression of RORγt target genes, notably Il17a, Il17f, Il23r, Ltb4r1,Ccr6.FGIN-1-27 protected mice against EAE, induced amino acid starvation response (AAR), FGIN-1-27 produced anti-anxiety and anti-panic effects in non-mammalian models.
• CAS Number: [142720-24-9]
• MW: 436.60458
• SMILES: FC1C=CC(C2=C(CC(N(CCCCCC)CCCCCC)=O)C3C(=CC=CC=3)N2)=CC=1
• Formula: C₂₈H₃₇N₂OF
• Note: For research use only
• Expiration Date: 12 months from date of receipt.