FG 7142

• Catalog Number: orb1309678
• Category: Small Molecules
• Description: FG 7142
• CAS Number: 78538-74-6
• Purity: 98.81%
• MW: 225.25
• SMILES: C(NC)(=O)C=1C=C2C=3C(NC2=CN1)=CC=CC3
• Formula: C₁₃H₁₁N₃O
• Biological Activity: FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.