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Catalog Number | orb1309678 |
---|---|
Category | Small Molecules |
Description | FG 7142 |
CAS Number | 78538-74-6 |
Purity | 98.81% |
MW | 225.25 |
SMILES | CNC(=O)c1cc2c(cn1)[nH]c1ccccc21 |
Formula | C13H11N3O |
Biological Activity | FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |