Fasudil mesylate

• Catalog Number: orb2566273
• Category: Small Molecules
• Description: Fasudil mesylate (HA-1077; AT877) is a nonspecific, orally active inhibitor of RhoA/ROCK, exhibiting additional inhibitory effects on protein kinases with a K i of 0.33 μM for ROCK1. It shows IC 50 values of 0.158 μM for ROCK2, and 4.58 μM, 12.30 μM, and 1.650 μM for PKA, PKC, and PKG, respectively. Furthermore, Fasudil mesylate acts as a potent Ca 2+ channel antagonist and vasodilator, enhancing its pharmacological profile [1] [2] [3] [4] [5] [6].
• CAS Number: 1001206-62-7
• Purity: 98.00%
• MW: 387.47
• SMILES: S(C)(=O)(=O)O.S(=O)(=O)(C=1C2=C(C=CC1)C=NC=C2)N3CCCNCC3
• Formula: C₁₅H₂₁N₃O₅S₂
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.