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Catalog Number | orb1298623 |
---|---|
Category | Small Molecules |
Description | (E/Z)-IT-603 |
CAS Number | 292168-90-2 |
Purity | 98.97% |
MW | 329.17 |
SMILES | C(C1=C(O)C(OC)=CC(Br)=C1)=C2C(=O)NC(=S)N2 |
Formula | C11H9BrN2O3S |
Biological Activity | (E/Z)-IT-603 is a cell-permeable c-Rel inhibitor (IC50: 3μM). IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity. |
Storage | Store at -20°C for 12 months. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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