EX-527

• Catalog Number: orb1713921
• Category: Small Molecules
• Description: SIRT1 inhibitor
• CAS Number: 49843-98-3
• Form/Appearance: Light Yellow Solid
• Purity: > 98% (TLC), NMR conforms
• MW: 248.7
• SMILES: C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
• Formula: C₁₃H₁₃ClN₂O
• Hazard Information: Classification: Harmful- May be harmful if inhaled, swallowed, or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with skin and eyes Hazard Statements: H301 – Toxic if swallowed H319 – Causes serious eye irritation Precautionary Statements: P301 + P310 – If swallowed: Immediately call a POSION Center P305 + P351 + P338: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
• Solubility (25°C): Soluble in 18 mg/ml DMSO or 10 mg/ml Ethanol
• Source: Synthetic
• Storage: -20°C
• Alternative names: 6-Chloro-2,3,4,9-tetrahydro-1Hcarbazole-1-carboxam
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of EX-527, a SIRT1 inhibitor. CAS #: 49843-98-3. Molecular Formula: C13H13ClN2O. Molecular Weight: 248.7 g/mol.