Etravirine

• Catalog Number: orb1305326
• Category: Small Molecules
• Description: Etravirine
• CAS Number: 269055-15-4
• Purity: 99.56%
• MW: 435.28
• SMILES: O(C1=NC(NC2=CC=C(C#N)C=C2)=NC(N)=C1Br)C3=C(C)C=C(C#N)C=C3C
• Formula: C₂₀H₁₅BrN₆O
• Biological Activity: Etravirine (R165335) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor. Etravirine is designed to be active against HIV isolates with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs. It can bind the enzyme reverse transcriptase (RT) in multiple conformations, both for native and mutant RT, thereby blocking the enzymatic activity of RT.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.