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Catalog Number | orb1691891 |
---|---|
Category | Small Molecules |
Description | Etoposide phosphate disodium |
CAS Number | 122405-33-8 |
Purity | 98% |
MW | 712.5 |
SMILES | [Na].[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OP(O)(O)=O)c(OC)c1)c1cc3OCOc3cc1[C@H]2O[C@@H]1O[C@]2([H])CO[C@@H](C)O[C@@]2([H])[C@H](O)[C@H]1OjcExt:v:0:0 |
Formula | C29H31Na2O16P |
Biological Activity | Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, functions as a potent chemotherapeutic agent by selectively inhibiting topoisomerase II, hindering the re-ligation of DNA strands. It is regarded as the active equivalent of etoposide, effectively inducing cell cycle arrest, apoptosis, and autophagy in cancer cells. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |