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Catalog Number | orb1301219 |
---|---|
Category | Small Molecules |
Description | Enzalutamide |
CAS Number | 915087-33-1 |
Purity | 99.70% |
MW | 464.44 |
SMILES | S=C1N(C(C)(C)C(=O)N1C2=CC(C(F)(F)F)=C(C#N)C=C2)C3=CC(F)=C(C(NC)=O)C=C3 |
Formula | C21H16F4N4O2S |
Biological Activity | Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly used in the treatment of desmoplasia-resistant prostate cancer. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[915087-33-1] | |
464.4359528 | |
C21H16F4N4O2S |