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Catalog Number | orb1709330 |
---|---|
Category | Small Molecules |
Description | Eltanexor Z-isomer |
CAS Number | 1642300-78-4 |
MW | 428.29 |
SMILES | C(F)(F)(F)C=1C=C(C=C(C(F)(F)F)C1)C2=NN(/C=C(\C(N)=O)/C=3C=NC=NC3)C=N2 |
Formula | C17H10F6N6O |
Biological Activity | Eltanexor Z-isomer exhibits different inhibitory effects on Z138, MM15, 3T3 cell lines, with IC50s of 100 nM-50 μM, 30 μM, respectively.Eltanexor Z-isomer is the less active isomer of KPT-8602. KPT-8602 is a potent CRM1 inhibitor. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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