Eltanexor

• Catalog Number: orb1309507
• Category: Small Molecules
• Description: Eltanexor
• CAS Number: 1642300-52-4
• Purity: 98%
• MW: 428.29
• SMILES: C(F)(F)(F)C=1C=C(C=C(C(F)(F)F)C1)C2=NN(/C=C(/C(N)=O)\C=3C=NC=NC3)C=N2
• Formula: C₁₇H₁₀F₆N₆O
• Biological Activity: Eltanexor (ONO-7706) is an orally active exportin-1 (XPO1) inhibitor. It has effective anti-leukemic activity. Eltanexor inhibits XPO1-dependent nuclear export (EC50=60.9 nM) by directly targeting XPO1. Eltanexor causes caspase-dependent apoptosis in a panel of leukemic cell lines.
• Storage: Store at -20°C for 12 months.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.