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EHMT2 (M) Antibody, Rabbit Polyclonal
Catalog Number: orb67069
| Catalog Number | orb67069 |
|---|---|
| Category | Antibodies |
| Description | Rabbit polyclonal to EHMT2.Euchromatic histone-lysine N-methyltransferase 2 (EHMT2) belongs to the histone-lysinemethyltransferase family, Suvar3-9 subfamily. EHMT2 specifically mono-and dimethylates 'Lys-9' ofhistone H3 (H3K9me1 and H3K9me2, respectively) in euchromatin. H3K9me represents a specific tagfor epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT2also weakly methylates 'Lys-27' of histone H3 (H3K27me). In addition, EHMT2 is required for DNAmethylation, which is independent of its histone methyltransferase activity. Furthermore, EHMT2methylates non-histone proteins, including p53/TP53, CDYL, WIZ, ACIN1, DNMT1, HDAC1, ERCC6,KLF12 and itself. |
| Species/Host | Rabbit |
| Clonality | Polyclonal |
| Tested applications | WB |
| Reactivity | Human |
| Immunogen | middle region of human EHMT2 |
| Dilution range | WB:1:1000-1:5000 |
| Purity | Affinity purification |
| Conjugation | Unconjugated |
| MW | 132 |
| UniProt ID | Q96KQ7 |
| Storage | -20°C |
| Buffer/Preservatives | 0.01% NaN3 |
| Alternative names | anti-EHMT2 antibody,anti-Histonelysine Nmethyltran Read more... |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
Western blot analysis of total cell extracts from human Hela using EHMT2 antibody
