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Catalog Number | orb613908 |
---|---|
Category | Antibodies |
Description | Human monoclonal antibody to EGFR domain III |
Species/Host | Human |
Clonality | Monoclonal |
Clone Number | h-R3 (Nimotuzumab) |
Tested applications | Blocking, FC, IHC |
Reactivity | Human |
Isotype | IgG1 |
Immunogen | This antibody we generated by humanisation of the murine antibody R3, raised against EGFR purified from placenta membranes and A431 tumors. |
Concentration | 1 mg/ml |
Purity | Purified |
Conjugation | Unconjugated |
Target | EGFR domain III |
UniProt ID | P00533 |
Storage | Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. |
Buffer/Preservatives | PBS with 0.02% Proclin 300. |
Alternative names | ERBB-D3; ERBB1; HER1; PIG61; mENA; avian erythrobl Read more... |
Note | For research use only |
Application notes | This antibody binds to human EGFR and inhibits EGF-dependent clonogenic growth of NRK cells and completely blocks EGF stimulated autophosphorylation of the receptor (Fernandez 1992) |
Expiration Date | 12 months from date of receipt. |
Recombinant | |
Unconjugated |
Recombinant | |
Unconjugated |
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