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EDP-305
Catalog Number: orb1744190
| Catalog Number | orb1744190 |
|---|---|
| Category | Small Molecules |
| Description | EDP-305, an orally active, potent, and selective agonist of the farnesoid X receptor (FXR), exhibits EC50 values of 34 nM in chimeric FXR within CHO cells and 8 nM in full-length FXR in HEK cells. Demonstrating a potent and consistent antifibrotic effect, EDP-305 is utilized in research related to primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). |
| CAS Number | 1933507-63-1 |
| Purity | 98.00% |
| MW | 630.92 |
| SMILES | O[C@H]1[C@@]2([C@@]([C@]3(C)[C@]([C@H]1CC)(C[C@H](O)CC3)[H])(CC[C@@]4(C)[C@]2(CC[C@@]4([C@@H](CCNC(NS(=O)(=O)C5=CC=C(C(C)(C)C)C=C5)=O)C)[H])[H])[H])[H] |
| Formula | C36H58N2O5S |
| Biological Activity | EDP-305, an orally active, potent, and selective agonist of the farnesoid X receptor (FXR), exhibits EC50 values of 34 nM in chimeric FXR within CHO cells and 8 nM in full-length FXR in HEK cells. Demonstrating a potent and consistent antifibrotic effect, EDP-305 is utilized in research related to primary biliary cholangitis (PBC) and non-alcoholic steatohepatitis (NASH). |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
