DTHIB

• Catalog Number: orb1089349
• Category: Small Molecules
• Description: DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research.
• CAS Number: [897326-30-6]
• MW: 309.68
• SMILES: O=C(NC1=CC=C(F)C=C1)NC2=CC=C(Cl)C([N+]([O-])=O)=C2
• Formula: C₁₃H₉ClFN₃O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.