DSR-141562

• Catalog Number: orb1089425
• Category: Small Molecules
• Description: DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.
• CAS Number: [2007975-22-4]
• MW: 414.42
• SMILES: O=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4
• Formula: C₁₉H₂₅F₃N₄O₃
• Note: For research use only
• Expiration Date: 12 months from date of receipt.