DS-6051b

• Catalog Number: orb654659
• Category: Small Molecules
• Description: DS-6051b is a potent and selective ROS1 and TRK family inhibitor with IC50 of 0.207 nM, 0.622 nM and 0.980 nM against ROS1, NTRK1 and NTRK3. DS-6051b especially inhibits ROS1 G2032R and other crizotinib-resistant ROS1 mutants.
• CAS Number: [1505515-69-4]
• MW: 551.619
• SMILES: O=C(O)CCCCC(O)=O.C[C@@H](NC1=NN2C(C=C1)=NC=C2C3=CC=C(OC[C@H](N)C)C=C3)C4=CC=CC(F)=C4
• Formula: C₂₉H₃₄FN₅O₅
• Note: For research use only
• Expiration Date: 12 months from date of receipt.