DS-1205b free base

• Catalog Number: orb1089355
• Category: Small Molecules
• Description: DS-1205b free base is a potent and selective inhibitor of AXL kinase, with an IC50 of 1.3 nM. DS-1205b free base also inhibits MER, MET, and TRKA, with IC50s of 63, 104, and 407 nM, respectively. DS-1205b free base can inhibit cell migration in vitro and tumor growth in vivo.
• CAS Number: [1855860-24-0]
• MW: 735.8
• SMILES: O=C(C1=CN(CC2CCOCC2)C=C(C3=NC=C(C)C=C3)C1=O)NC4=CC=C(C5=CC(C6=CC=C(OC[C@@H]7OCCOC7)C(OC)=C6)=CN=C5N)C(F)=C4
• Formula: C₄₁H₄₂FN₅O₇
• Note: For research use only
• Expiration Date: 12 months from date of receipt.