Dovitinib (TKI258, CHIR258)

• Catalog Number: orb154678
• Category: Small Molecules
• Description: Dovitinib (TKI258, CHIR258) is a novel multi-target inhibitor for Flt3, c-Kit, FGFR1/3, VEGFR1/2/3, PDGFRα/β with IC50 of 1 nM, 2 nM, 8 nM/9 nM and 10 nM/13 nM/8 nM, 210 nM/27 nM respectively.
• CAS Number: [405169-16-6]
• MW: 392.4294
• SMILES: FC1=C([H])C([H])=C([H])C2=C1C([H])=C(C(N2N([H])[H])=O)C1=NC2C([H])=C([H])C(=C([H])C=2N1[H])N1C([H])([H])C([H])([H])N(C([H])([H])[H])C([H])([H])C1([H])[H]
• Formula: C₂₁H₂₁FN₆O
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Chemical structure of CHIR258